产品货号:
Z32355
中文名称:
Caspase 10/CASP10抗体
英文名称:
Anti-Caspase 10/CASP10 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-Caspase 10/CASP10 Antibody |
指标别名 | ALPS2;Apoptotic protease Mch 4;CASP 10;CASP10;Caspase 10;Caspase 10/p23/17/p12;Caspase10;FLICE2;ICE like apoptotic protease 4;MCH4 |
克隆性 | Monoclonal |
检验物种 | human |
应用范围 | WB,IHC,IP,FCM |
基因名称 | CASP10 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthesized peptide derived from human Caspase-10 |
实际分子量 | 59KD |
成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
纯化方式 | Affinity-chromatography |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Caspase-10 is an enzyme that,in humans,is encoded by the CASP10 gene.The Caspase 10 gene contains 11 exons and spans about 48kb.This gene is mapped to 2q33.1.It is transcribed in the centromere-to-telomere direction.This gene encodes a protein that is a member of the cysteine-aspartic acid protease(caspase) family.Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis.Caspases exist as inactive proenzymes that undergo proteolytic processing at conserved aspartic residues to produce two subunits,large and small,that dimerize to form the active enzyme.This protein cleaves and activates caspases 3 and 7,and the protein itself is processed by caspase 8.Mutations in this gene are associated with apoptosis defects seen in type II autoimmune lymphoproliferative syndrome.Three alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
Uniprot ID | Q92851 |
基因名全称 | Caspase-10 |
推荐稀释比 | Western blot (WB) 1:500~2000 Immunohistochemistry in paraffin section (IHC) 1:20~100 Immunocoprecipitation 1:20 Flow cytometry (FCM) 1:20 |
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